Hdh.sup.Q111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulati...
Hdh.sup.Q111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation
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Public Library of Science
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English
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Public Library of Science
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The HTT CAG expansion mutation causes Huntington's Disease and is associated with a wide range of cellular consequences, including altered metabolism. The mutant allele is expressed widely, in all tissues, but the striatum and cortex are especially vulnerable to its effects. To more fully understand this tissue-specificity, early in the disease pro...
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Full title
Hdh.sup.Q111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation
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TN_cdi_gale_infotracmisc_A426228353
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A426228353
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0134465
