Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine:...
Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers
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Springer
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English
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Springer
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Rationale Histamine H.sub.1 antagonists have hypnotic, appetite-promoting, and sedative side effects. Most second-generation antipsychotics have potent antagonistic effects on histamine H.sub.1 receptor (H1R). Positron emission tomography (PET) can measure the H1R occupancy (H1RO) in vivo, although there are no reports regarding antipsychotics. Obj...
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Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers
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TN_cdi_gale_infotracmisc_A427857124
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A427857124
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0033-3158
DOI
10.1007/s00213-015-4002-2