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Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine:...

Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine:...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A427857124

Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

About this item

Full title

Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Publisher

Springer

Journal title

Psychopharmacology, 2015-10, Vol.232 (19), p.3497

Language

English

Formats

Publication information

Publisher

Springer

More information

Scope and Contents

Contents

Rationale Histamine H.sub.1 antagonists have hypnotic, appetite-promoting, and sedative side effects. Most second-generation antipsychotics have potent antagonistic effects on histamine H.sub.1 receptor (H1R). Positron emission tomography (PET) can measure the H1R occupancy (H1RO) in vivo, although there are no reports regarding antipsychotics. Obj...

Alternative Titles

Full title

Histamine H.sub.1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A427857124

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A427857124

Other Identifiers

ISSN

0033-3158

DOI

10.1007/s00213-015-4002-2

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