Signal integration by [Ca.sup.2+] regulates intestinal stem-cell activity
Signal integration by [Ca.sup.2+] regulates intestinal stem-cell activity
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Publisher
Nature Publishing Group
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Language
English
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Nature Publishing Group
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Contents
Somatic stem cells maintain tissue homeostasis by dynamically adjusting proliferation and differentiation in response to stress and metabolic cues. Here we identify [Ca.sup.2+] signalling as a central regulator of intestinal stem cell (ISC) activity in Drosophila. We show that dietary L-glutamate stimulates ISC division and gut growth. The metabotr...
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Full title
Signal integration by [Ca.sup.2+] regulates intestinal stem-cell activity
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TN_cdi_gale_infotracmisc_A437223672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A437223672
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature16170
