Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA.sub.2 in Mouse Intestinal Epitheli...
Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA.sub.2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia
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Public Library of Science
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English
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Public Library of Science
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Lysophosphatidic acid (LPA) acts on LPA.sub.2 receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA.sub.2 attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA.sub.2 alone can lead to malignant transformation in the intestinal tract has not been s...
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Full title
Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA.sub.2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia
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TN_cdi_gale_infotracmisc_A453418220
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A453418220
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0154527
