Cytochrome P450 1A2 Metabolizes 17[beta]-Estradiol to Suppress Hepatocellular Carcinoma
Cytochrome P450 1A2 Metabolizes 17[beta]-Estradiol to Suppress Hepatocellular Carcinoma
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Author / Creator
Ren, Jianwai , Chen, George G , Liu, Yi , Su, Xianwei , Hu, Baoguang , Leung, Billy C. S , Wang, Y , Ho, Rocky L. K , Yang, Shengli , Lu, Gang , Lee, C. G and Lai, Paul B. S
Publisher
Public Library of Science
Journal title
Language
English
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Publisher
Public Library of Science
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Contents
Hepatocellular carcinoma (HCC) occurs more frequently in men than in women. It is commonly agreed that estrogen plays important roles in suppressing HCC development, however, the underlying mechanism remains largely unknown. Since estrogen is mainly metabolized in liver and its metabolites affect cell proliferation, we sought to investigate if the...
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Full title
Cytochrome P450 1A2 Metabolizes 17[beta]-Estradiol to Suppress Hepatocellular Carcinoma
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TN_cdi_gale_infotracmisc_A453447926
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A453447926
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0153863
