Ankyrin-B is a PI3P effector that promotes polarized [alpha]5[beta]1-integrin recycling via recruiti...
Ankyrin-B is a PI3P effector that promotes polarized [alpha]5[beta]1-integrin recycling via recruiting RabGAP1L to early endosomes
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eLife Science Publications, Ltd
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English
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eLife Science Publications, Ltd
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Endosomal membrane trafficking requires coordination between phosphoinositide lipids, Rab GTPases, and microtubule-based motors to dynamically determine endosome identity and promote long-range organelle transport. Here we report that ankyrin-B (AnkB), through integrating all three systems, functions as a critical node in the protein circuitry unde...
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Full title
Ankyrin-B is a PI3P effector that promotes polarized [alpha]5[beta]1-integrin recycling via recruiting RabGAP1L to early endosomes
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TN_cdi_gale_infotracmisc_A468573976
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A468573976
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.20417
