Inhibition of Hypoxia-Inducible Factor-1[alpha] Protein Synthesis by DNA Damage Inducing Agents
Inhibition of Hypoxia-Inducible Factor-1[alpha] Protein Synthesis by DNA Damage Inducing Agents
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Public Library of Science
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English
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Public Library of Science
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Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor that is composed of a hypoxia-inducible [alpha] subunit (HIF-1[alpha] and HIF-2[alpha]) and a constitutively expressed [beta] subunit (HIF-1[beta]). HIF mediates the adaptation of cells and tissues to low oxygen concentrations. It also plays an important role in tumorigenesis an...
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Full title
Inhibition of Hypoxia-Inducible Factor-1[alpha] Protein Synthesis by DNA Damage Inducing Agents
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TN_cdi_gale_infotracmisc_A473896859
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A473896859
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0010522
