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Regulatory T Cell Suppression of Gag-Specific CD8.sup.+ T Cell Polyfunctional Response After Therape...

Regulatory T Cell Suppression of Gag-Specific CD8.sup.+ T Cell Polyfunctional Response After Therape...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A473908431

Regulatory T Cell Suppression of Gag-Specific CD8.sup.+ T Cell Polyfunctional Response After Therapeutic Vaccination of HIV-1-Infected Patients on ART

About this item

Full title

Regulatory T Cell Suppression of Gag-Specific CD8.sup.+ T Cell Polyfunctional Response After Therapeutic Vaccination of HIV-1-Infected Patients on ART

Publisher

Public Library of Science

Journal title

PloS one, 2010-03, Vol.5 (3), p.e9852

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

We tested the hypothesis that therapeutic vaccination against HIV-1 can increase the frequency and suppressive function of regulatory, CD4.sup.+ T cells (Treg), thereby masking enhancement of HIV-1-specific CD8.sup.+ T cell response. HIV-1-infected subjects on antiretroviral therapy (N = 17) enrolled in a phase I therapeutic vaccine trial received...

Alternative Titles

Full title

Regulatory T Cell Suppression of Gag-Specific CD8.sup.+ T Cell Polyfunctional Response After Therapeutic Vaccination of HIV-1-Infected Patients on ART

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A473908431

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A473908431

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0009852

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