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Intracellular Trafficking of the Amyloid [beta]-Protein Precursor Regulated by Novel Function of X11...

Intracellular Trafficking of the Amyloid [beta]-Protein Precursor Regulated by Novel Function of X11...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A476884441

Intracellular Trafficking of the Amyloid [beta]-Protein Precursor Regulated by Novel Function of X11-Like

About this item

Full title

Intracellular Trafficking of the Amyloid [beta]-Protein Precursor Regulated by Novel Function of X11-Like

Publisher

Public Library of Science

Journal title

PloS one, 2011-07, Vol.6 (7), p.e22108

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Background Amyloid [beta] (A[beta]), a causative peptide of Alzheimer's disease, is generated by intracellular metabolism of amyloid [beta]-protein precursor (APP). In general, mature APP (mAPP, N- and O-glycosylated form) is subject to successive cleavages by [alpha]- or [beta]-, and [gamma]-secretases in the late protein secretory pathway and/or...

Alternative Titles

Full title

Intracellular Trafficking of the Amyloid [beta]-Protein Precursor Regulated by Novel Function of X11-Like

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A476884441

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A476884441

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0022108

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