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An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1[beta]...

An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1[beta]...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A476891525

An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1[beta] Secretion

About this item

Full title

An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1[beta] Secretion

Publisher

Public Library of Science

Journal title

PloS one, 2011-05, Vol.6 (5), p.e19829

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

The generation of diversity and plasticity of transcriptional programs are key components of effective vertebrate immune responses. The role of Alternative Splicing has been recognized, but it is underappreciated and poorly understood as a critical mechanism for the regulation and fine-tuning of physiological immune responses. Here we report the ge...

Alternative Titles

Full title

An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1[beta] Secretion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A476891525

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A476891525

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0019829

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