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Identifying Quantitative Trait Loci Affecting Resistance to Congenital Hypothyroidism in 129.sup.+Te...

Identifying Quantitative Trait Loci Affecting Resistance to Congenital Hypothyroidism in 129.sup.+Te...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477017160

Identifying Quantitative Trait Loci Affecting Resistance to Congenital Hypothyroidism in 129.sup.+Ter/SvJcl Strain Mice

About this item

Full title

Identifying Quantitative Trait Loci Affecting Resistance to Congenital Hypothyroidism in 129.sup.+Ter/SvJcl Strain Mice

Publisher

Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e31035

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Tyrosylprotein sulfotransferase 2 (TPST2) is one of the enzymes responsible for tyrosine O-sulfation and catalyzes the sulfation of the specific tyrosine residue of thyroid stimulating hormone receptor (TSHR). Since this modification is indispensable for the activation of TSH signaling, a non-functional TPST2 mutation (Tpst2.sup.grt) in DW/J-grt mi...

Alternative Titles

Full title

Identifying Quantitative Trait Loci Affecting Resistance to Congenital Hypothyroidism in 129.sup.+Ter/SvJcl Strain Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A477017160

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477017160

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0031035

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