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The Increased Expression of Integrin [alpha]6 Enhances Drug Resistance in EVI1.sup.high Leukemia

The Increased Expression of Integrin [alpha]6 Enhances Drug Resistance in EVI1.sup.high Leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477045028

The Increased Expression of Integrin [alpha]6 Enhances Drug Resistance in EVI1.sup.high Leukemia

About this item

Full title

The Increased Expression of Integrin [alpha]6 Enhances Drug Resistance in EVI1.sup.high Leukemia

Publisher

Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e30706

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Ecotropic viral integration site-1 (EVI1) is one of the candidate oncogenes for human acute myeloid leukemia (AML) with chromosomal alterations at 3q26. High EVI1 expression (EVI1.sup.high) is a risk factor for AML with poor outcome. Using DNA microarray analysis, we previously identified that integrin [alpha]6 (ITGA6) was upregulated over 10-fold...

Alternative Titles

Full title

The Increased Expression of Integrin [alpha]6 Enhances Drug Resistance in EVI1.sup.high Leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A477045028

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477045028

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0030706

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