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Multi-Level Interactions between the Nuclear Receptor TR[alpha]1 and the WNT Effectors [beta]-Cateni...

Multi-Level Interactions between the Nuclear Receptor TR[alpha]1 and the WNT Effectors [beta]-Cateni...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477149861

Multi-Level Interactions between the Nuclear Receptor TR[alpha]1 and the WNT Effectors [beta]-Catenin/Tcf4 in the Intestinal Epithelium

About this item

Full title

Multi-Level Interactions between the Nuclear Receptor TR[alpha]1 and the WNT Effectors [beta]-Catenin/Tcf4 in the Intestinal Epithelium

Publisher

Public Library of Science

Journal title

PloS one, 2012-04, Vol.7 (4), p.e34162

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Intestinal homeostasis results from complex cross-regulation of signaling pathways; their alteration induces intestinal tumorigenesis. Previously, we found that the thyroid hormone nuclear receptor TR[alpha]1 activates and synergizes with the WNT pathway, inducing crypt cell proliferation and promoting tumorigenesis. Here, we investigated the mecha...

Alternative Titles

Full title

Multi-Level Interactions between the Nuclear Receptor TR[alpha]1 and the WNT Effectors [beta]-Catenin/Tcf4 in the Intestinal Epithelium

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A477149861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A477149861

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0034162

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