Hyperoxia Exposure Impairs Nephrogenesis in the Neonatal Rat: Role of HIF-1[alpha]
Hyperoxia Exposure Impairs Nephrogenesis in the Neonatal Rat: Role of HIF-1[alpha]
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Publisher
Public Library of Science
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Language
English
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Public Library of Science
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Preterm neonates are exposed at birth to high oxygen concentrations relative to the intrauterine environment. We have previously shown in a rat model that a hyperoxic insult results in a reduced nephron number in adulthood. Therefore, the aim of this study was to determine the effects of transient neonatal hyperoxia exposure on nephrogenesis. Sprag...
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Full title
Hyperoxia Exposure Impairs Nephrogenesis in the Neonatal Rat: Role of HIF-1[alpha]
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TN_cdi_gale_infotracmisc_A478243014
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478243014
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0082421
