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CD4.sup.+ T Cells Are as Protective as CD8.sup.+ T Cells against Rickettsia typhi Infection by Activ...

CD4.sup.+ T Cells Are as Protective as CD8.sup.+ T Cells against Rickettsia typhi Infection by Activ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478272765

CD4.sup.+ T Cells Are as Protective as CD8.sup.+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

About this item

Full title

CD4.sup.+ T Cells Are as Protective as CD8.sup.+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

Publisher

Public Library of Science

Journal title

PLoS neglected tropical diseases, 2016-11, Vol.10 (11)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1.sup.-/- mice upon Rickettsia typhi infection. Here, we show that CD4.sup.+ T.sub.H 1 cel...

Alternative Titles

Full title

CD4.sup.+ T Cells Are as Protective as CD8.sup.+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A478272765

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478272765

Other Identifiers

ISSN

1935-2727

DOI

10.1371/journal.pntd.0005089

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