Silencing Mutated [beta]-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenoc...
Silencing Mutated [beta]-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R
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Public Library of Science
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English
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Public Library of Science
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Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating [beta]-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the Wnt/[beta]-catenin signaling pathway seems to play a major role in ACC aggressiveness, and...
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Silencing Mutated [beta]-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R
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TN_cdi_gale_infotracmisc_A478401264
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478401264
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0055743
