The Newly Developed CRF.sub.1-Receptor Antagonists, NGD 98-2 and NGD 9002, Suppress Acute Stress-Ind...
The Newly Developed CRF.sub.1-Receptor Antagonists, NGD 98-2 and NGD 9002, Suppress Acute Stress-Induced Stimulation of Colonic Motor Function and Visceral Hypersensitivity in Rats
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Public Library of Science
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Language
English
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Public Library of Science
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Contents
Corticotropin releasing factor receptor 1 (CRF.sub.1) is the key receptor that mediates stress-related body responses. However to date there are no CRF.sub.1 antagonists that have shown clinical efficacy in stress-related diseases. We investigated the inhibitory effects of a new generation, topology 2 selective CRF.sub.1 antagonists, NGD 98-2 and N...
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Full title
The Newly Developed CRF.sub.1-Receptor Antagonists, NGD 98-2 and NGD 9002, Suppress Acute Stress-Induced Stimulation of Colonic Motor Function and Visceral Hypersensitivity in Rats
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TN_cdi_gale_infotracmisc_A478404482
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478404482
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0073749
