Mutation or Loss of p53 Differentially Modifies TGF[beta] Action in Ovarian Cancer
Mutation or Loss of p53 Differentially Modifies TGF[beta] Action in Ovarian Cancer
About this item
Full title
Author / Creator
Publisher
Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
Public Library of Science
Subjects
More information
Scope and Contents
Contents
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transforming Growth Factor Beta (TGF[beta]) pathway is dysfunctional in various malignancies, including ovarian...
Alternative Titles
Full title
Mutation or Loss of p53 Differentially Modifies TGF[beta] Action in Ovarian Cancer
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A478797958
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478797958
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089553
