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Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-[gamma]

Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-[gamma]

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478798013

Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-[gamma]

About this item

Full title

Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-[gamma]

Publisher

Public Library of Science

Journal title

PloS one, 2014-02, Vol.9 (2), p.e89284

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Innate immune sensors such as Toll-like receptors (TLRs) differentially utilize adaptor proteins and additional molecular mediators to ensure robust and precise immune responses to pathogen challenge. Through a gain-of-function genetic screen, we identified the gamma catalytic subunit of protein phosphatase 1 (PP1-[gamma]) as a positive regulator o...

Alternative Titles

Full title

Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-[gamma]

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A478798013

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478798013

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0089284

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