Post translational changes to [alpha]-synuclein control iron and dopamine trafficking; a concept for...
Post translational changes to [alpha]-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease
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Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Contents
Parkinson's disease is a multifactorial neurodegenerative disorder, the aetiology of which remains elusive. The primary clinical feature of progressively impaired motor control is caused by a loss of midbrain substantia nigra dopamine neurons that have a high [alpha]-synuclein ([alpha]-syn) and iron content. [alpha]-Syn is a neuronal protein that i...
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Full title
Post translational changes to [alpha]-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease
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TN_cdi_gale_infotracmisc_A494769313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A494769313
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-017-0186-8
