Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Tra...
Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-[kappa]B in R-HepG2 Cell Line
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Publisher
Public Library of Science
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Language
English
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Public Library of Science
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Multidrug resistance(MDR)is one of the major reasons for failure in cancer chemotherapy and its suppression may increase the efficacy of therapy. The human multidrug resistance 1 (MDR1) gene encodes the plasma membrane P-glycoprotein (P-gp) that pumps various anti-cancer agents out of the cancer cell. R-HepG2 and MES-SA/Dx5 cells are doxorubicin in...
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Full title
Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-[kappa]B in R-HepG2 Cell Line
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TN_cdi_gale_infotracmisc_A498259065
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A498259065
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0040720
