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A novel region in the Ca.sub.V2.1 [alpha].sub.1 subunit C-terminus regulates fast synaptic vesicle f...

A novel region in the Ca.sub.V2.1 [alpha].sub.1 subunit C-terminus regulates fast synaptic vesicle f...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A500107927

A novel region in the Ca.sub.V2.1 [alpha].sub.1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

About this item

Full title

A novel region in the Ca.sub.V2.1 [alpha].sub.1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

Publisher

eLife Science Publications, Ltd

Journal title

eLife, 2017-08, Vol.6

Language

English

Formats

Publication information

Publisher

eLife Science Publications, Ltd

More information

Scope and Contents

Contents

In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is principally mediated by Ca.sub.V2.1 calcium channels (Ca.sub.V2.1) and is highly dependent on the physical distance between Ca.sub.V2.1 and synaptic vesicles (coupling). Although various active zone proteins are proposed to control coupling and abundance o...

Alternative Titles

Full title

A novel region in the Ca.sub.V2.1 [alpha].sub.1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A500107927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A500107927

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.28412

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