Genomic upregulation of cardiac Cav1.2[alpha] and NCX1 by estrogen in women
Genomic upregulation of cardiac Cav1.2[alpha] and NCX1 by estrogen in women
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Background Women have a higher risk of lethal arrhythmias than men in long QT syndrome type 2 (LQTS2), but the mechanisms remain uncertain due to the limited availability of healthy control human tissue. We have previously reported that in female rabbits, estrogen increases arrhythmia risk in drug-induced LQTS2 by upregulating L-type Ca.sup.2+ (I.s...
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Genomic upregulation of cardiac Cav1.2[alpha] and NCX1 by estrogen in women
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TN_cdi_gale_infotracmisc_A511282530
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A511282530
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2042-6410
E-ISSN
2042-6410
DOI
10.1186/s13293-017-0148-4
