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Effects of peroxisome proliferator activated receptors -[gamma] and -[alpha] agonists on cochlear pr...

Effects of peroxisome proliferator activated receptors -[gamma] and -[alpha] agonists on cochlear pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A516065893

Effects of peroxisome proliferator activated receptors -[gamma] and -[alpha] agonists on cochlear protection from oxidative stress

About this item

Full title

Effects of peroxisome proliferator activated receptors -[gamma] and -[alpha] agonists on cochlear protection from oxidative stress

Publisher

Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0188596

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabetes and dyslipidemia. These agents target the peroxisome proliferator-activated receptors, PPAR[gamm...

Alternative Titles

Full title

Effects of peroxisome proliferator activated receptors -[gamma] and -[alpha] agonists on cochlear protection from oxidative stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A516065893

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A516065893

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0188596

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