Hippo, TGF-[beta], and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila e...
Hippo, TGF-[beta], and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection
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Public Library of Science
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English
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Public Library of Science
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Cytokine signaling is responsible for coordinating conserved epithelial regeneration and immune responses in the digestive tract. In the Drosophila midgut, Upd3 is a major cytokine, which is induced in enterocytes (EC) and enteroblasts (EB) upon oral infection, and initiates intestinal stem cell (ISC) dependent tissue repair. To date, the genetic n...
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Hippo, TGF-[beta], and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection
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TN_cdi_gale_infotracmisc_A516767038
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A516767038
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ISSN
1553-7390
DOI
10.1371/journal.pgen.1007091
