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SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing k...

SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing k...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A520665833

SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing kinase by modulating SRF transcriptional activity in vascular smooth muscle cells

About this item

Full title

SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing kinase by modulating SRF transcriptional activity in vascular smooth muscle cells

Publisher

Public Library of Science

Journal title

PloS one, 2017-12, Vol.12 (12), p.e0190191

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Vascular smooth muscle cell (VSMC) phenotypic modulation is characterized by the downregulation of SMC actin cytoskeleton proteins. Our published study shows that depletion of SM22[alpha] (aka SM22, Transgelin, an actin cytoskeleton binding protein) promotes inflammation in SMCs by activating NF-[kappa]B signal pathways both in cultured VSMCs and i...

Alternative Titles

Full title

SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing kinase by modulating SRF transcriptional activity in vascular smooth muscle cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A520665833

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A520665833

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0190191

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