SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing k...
SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing kinase by modulating SRF transcriptional activity in vascular smooth muscle cells
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Public Library of Science
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English
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Public Library of Science
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Vascular smooth muscle cell (VSMC) phenotypic modulation is characterized by the downregulation of SMC actin cytoskeleton proteins. Our published study shows that depletion of SM22[alpha] (aka SM22, Transgelin, an actin cytoskeleton binding protein) promotes inflammation in SMCs by activating NF-[kappa]B signal pathways both in cultured VSMCs and i...
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SM22[alpha] suppresses cytokine-induced inflammation and the transcription of NF-[kappa]B inducing kinase by modulating SRF transcriptional activity in vascular smooth muscle cells
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TN_cdi_gale_infotracmisc_A520665833
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A520665833
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0190191