Design and application of a novel PNA probe for the detection at single cell level of JAK2V617Fmutat...
Design and application of a novel PNA probe for the detection at single cell level of JAK2V617Fmutation in Myeloproliferative Neoplasms
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Background Mutation(s) of the JAK2 gene (V617F) has been described in a significant proportion of Philadelphia negative Myeloproliferative Neoplasms (MPN) patients and its detection is now a cornerstone in the diagnostic algorithm. Methods We developed a novel assay based on peptide nucleic acid (PNA) technology coupled to immuno-fluorescence micro...
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Design and application of a novel PNA probe for the detection at single cell level of JAK2V617Fmutation in Myeloproliferative Neoplasms
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TN_cdi_gale_infotracmisc_A534612664
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A534612664
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1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-13-348
