Exclusive dependence of IL-10R[alpha] signalling on intestinal microbiota homeostasis and control of...
Exclusive dependence of IL-10R[alpha] signalling on intestinal microbiota homeostasis and control of whipworm infection
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Author / Creator
Duque-Correa, María A , Karp, Natasha A , McCarthy, Catherine , Forman, Simon , Goulding, David , Sankaranarayanan, Geetha , Jenkins, Timothy P , Reid, Adam J , Cambridge, Emma L , Ballesteros Reviriego, Carmen , Müller, Werner , Cantacessi, Cinzia , Dougan, Gordon , Grencis, Richard K and Berriman, Matthew
Publisher
Public Library of Science
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Language
English
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Public Library of Science
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Contents
The whipworm Trichuris trichiura is a soil-transmitted helminth that dwells in the epithelium of the caecum and proximal colon of their hosts causing the human disease, trichuriasis. Trichuriasis is characterized by colitis attributed to the inflammatory response elicited by the parasite while tunnelling through intestinal epithelial cells (IECs)....
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Full title
Exclusive dependence of IL-10R[alpha] signalling on intestinal microbiota homeostasis and control of whipworm infection
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TN_cdi_gale_infotracmisc_A571883359
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A571883359
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ISSN
1553-7366
DOI
10.1371/journal.ppat.1007265