IRE1[alpha] governs cytoskeleton remodelling and cell migration through a direct interaction with fi...
IRE1[alpha] governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
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Publisher
Nature Publishing Group
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English
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Nature Publishing Group
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Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer IRE1[alpha]. Filamin A is an actin crosslinking factor involved in cytoskeleton remodelling. We show that IRE1[alpha] controls...
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Full title
IRE1[alpha] governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
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TN_cdi_gale_infotracmisc_A572730130
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A572730130
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ISSN
1465-7392
DOI
10.1038/s41556-018-0141-0
