De novo NAD.sup.+ biosynthetic impairment in acute kidney injury in humans
De novo NAD.sup.+ biosynthetic impairment in acute kidney injury in humans
About this item
Full title
Author / Creator
Publisher
Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Nicotinamide adenine dinucleotide (NAD.sup.+) extends longevity in experimental organisms, raising interest in its impact on human health. De novo NAD.sup.+ biosynthesis from tryptophan is evolutionarily conserved yet considered supplanted among higher species by biosynthesis from nicotinamide (NAM). Here we show that a bottleneck enzyme in de novo...
Alternative Titles
Full title
De novo NAD.sup.+ biosynthetic impairment in acute kidney injury in humans
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A572904647
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A572904647
Other Identifiers
ISSN
1078-8956
DOI
10.1038/s41591-018-0138-z
