Can GABA turn pancreatic [alpha]-cells into [beta]-cells?
Can GABA turn pancreatic [alpha]-cells into [beta]-cells?
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Nature Publishing Group
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English
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Nature Publishing Group
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Contents
The neurotransmitter GABA has been shown to induce the transdifferentiation of [alpha]-cells into [beta]-cells, restoring normoglycaemia in a mouse model of diabetes mellitus. A recent paper by Amanda Ackermann and colleagues, however, failed to reproduce these findings. Here, we discuss the discrepant findings and propose a systematic approach to...
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Can GABA turn pancreatic [alpha]-cells into [beta]-cells?
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TN_cdi_gale_infotracmisc_A573026687
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A573026687
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ISSN
1759-5029
DOI
10.1038/s41574-018-0101-6
