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NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A576552536

NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

About this item

Full title

NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

Publisher

Nature Publishing Group

Journal title

Nature cell biology, 2019-03, Vol.21 (3), p.397

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD.sup.+ metabolism influences both tissue ageing and cancer. However, the role of NAD.sup.+ metabolis...

Alternative Titles

Full title

NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A576552536

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A576552536

Other Identifiers

ISSN

1465-7392

DOI

10.1038/s41556-019-0287-4

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