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Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[...

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A581412796

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[beta] activities

About this item

Full title

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[beta] activities

Publisher

BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2019-01, Vol.21 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Background Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cells enter the circulation to gain access to distant tissues, but how this fluid microenvironment influences cancer cell biology is p...

Alternative Titles

Full title

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[beta] activities

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A581412796

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A581412796

Other Identifiers

ISSN

1465-5411

DOI

10.1186/s13058-018-1071-2

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