Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[...
Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[beta] activities
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Background Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cells enter the circulation to gain access to distant tissues, but how this fluid microenvironment influences cancer cell biology is p...
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Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3[beta] activities
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TN_cdi_gale_infotracmisc_A581412796
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A581412796
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ISSN
1465-5411
DOI
10.1186/s13058-018-1071-2