Direct modulation of myelin-autoreactive [CD4.sup.+] and [CD8.sup.+] T cells in EAE mice by a tolero...
Direct modulation of myelin-autoreactive [CD4.sup.+] and [CD8.sup.+] T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, cD47 and multiple regulatory molecules
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Publisher
Dove Medical Press Limited
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Language
English
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Dove Medical Press Limited
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Purpose: Numerous nanomaterials have been reported in the treatment of multiple sclerosis or experimental autoimmune encephalomyelitis (EAE). But most of these nanoscale therapeutics deliver myelin antigens together with toxins or cytokines and underlay the cellular uptake and induction of tolerogenic antigen-presenting cells by which they indirect...
Alternative Titles
Full title
Direct modulation of myelin-autoreactive [CD4.sup.+] and [CD8.sup.+] T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, cD47 and multiple regulatory molecules
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TN_cdi_gale_infotracmisc_A583487967
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A583487967
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ISSN
1178-2013
DOI
10.2147/IJN.S164500
