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Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP...

Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A597858838

Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP regulation

About this item

Full title

Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP regulation

Publisher

Spandidos Publications

Journal title

Molecular medicine reports, 2019-08, Vol.20 (2)

Language

English

Formats

Publication information

Publisher

Spandidos Publications

More information

Scope and Contents

Contents

Voltage-gated sodium channel [beta]2 (Nav[beta]2), as an unconventional substrate of [beta]-site amyloid precursor protein cleaving enzyme 1, is involved in regulating the neuronal surface expression of sodium channels. A previous study demonstrated that knockdown of Nav[beta]2 protected neurons and induced spatial cognition improvement by partiall...

Alternative Titles

Full title

Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP regulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A597858838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A597858838

Other Identifiers

ISSN

1791-2997

DOI

10.3892/mmr.2019.10406

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