Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP...
Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP regulation
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Author / Creator
Hu, Tao , Li, Shan-Shan , Lu, Min-Nan , Zhang, Li , Chen, Bo , Mao, Rui , Mei, Rong , Tan, Ya-Xin , Li, Shan and Xiyang, Yan-Bin
Publisher
Spandidos Publications
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Language
English
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Spandidos Publications
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Contents
Voltage-gated sodium channel [beta]2 (Nav[beta]2), as an unconventional substrate of [beta]-site amyloid precursor protein cleaving enzyme 1, is involved in regulating the neuronal surface expression of sodium channels. A previous study demonstrated that knockdown of Nav[beta]2 protected neurons and induced spatial cognition improvement by partiall...
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Full title
Neuroprotection induced by Nav[beta]2-knockdown in APP/PS1 transgenic neurons is associated with NEP regulation
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TN_cdi_gale_infotracmisc_A597858838
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A597858838
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ISSN
1791-2997
DOI
10.3892/mmr.2019.10406