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A PDGFR[beta]-PI3K signaling axis mediates periosteal cell activation during fracture healing

A PDGFR[beta]-PI3K signaling axis mediates periosteal cell activation during fracture healing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A604275415

A PDGFR[beta]-PI3K signaling axis mediates periosteal cell activation during fracture healing

About this item

Full title

A PDGFR[beta]-PI3K signaling axis mediates periosteal cell activation during fracture healing

Publisher

Public Library of Science

Journal title

PloS one, 2019-10, p.e0223846

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Insufficient and delayed fracture healing remain significant public health problems with limited therapeutic options. Phosphoinositide 3-kinase (PI3K) signaling, a major pathway involved in regulation of fracture healing, promotes proliferation, migration, and differentiation of osteoprogenitors. We have recently reported that knock-in mice with a...

Alternative Titles

Full title

A PDGFR[beta]-PI3K signaling axis mediates periosteal cell activation during fracture healing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A604275415

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A604275415

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0223846

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