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Development and characterization of cellular biosensors for HTS of erythroid differentiation inducer...

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A606964024

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of [gamma]-globin and [beta]-globin gene promoters

About this item

Full title

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of [gamma]-globin and [beta]-globin gene promoters

Publisher

Springer

Journal title

Analytical and bioanalytical chemistry, 2019-11, Vol.411 (29), p.7669

Language

English

Formats

Publication information

Publisher

Springer

More information

Scope and Contents

Contents

There is a general agreement that pharmacologically mediated stimulation of human [gamma]-globin gene expression and increase of production of fetal hemoglobin (HbF) is a potential therapeutic approach in the experimental therapy of [beta]-thalassemia and sickle cell anemia. Here, we report the development and characterization of cellular biosensor...

Alternative Titles

Full title

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of [gamma]-globin and [beta]-globin gene promoters

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A606964024

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A606964024

Other Identifiers

ISSN

1618-2642

DOI

10.1007/s00216-019-01959-z

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