Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthio...
Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates
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Momin Khan, Momin Khan , Munir Ur Rehman, Munir Ur Rehman , Naveed Qadir, Naveed Qadir , Muhammad Ashraf, Muhammad Ashraf , Tayaba Ismail, Tayaba Ismail , Muhammad Ismail, Muhammad Ismail , Kanwal, Kanwal , Uzma Salar, Uzma Salar and Khalid Mohammed Khan and Shahnaz Perveen, Khalid Mohammed Khan and Shahnaz Perveen
Publisher
Knowledge Bylanes
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English
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Knowledge Bylanes
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5-Arylidene-N,N-diethylthiobarbiturates 1-25 were evaluated for their potential against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes and displayed varying degree of inhibition. Based on the IC50 values, compound 6 (IC50 = 92.51 and#177; 0.01 and#181;M) was the only active compound against acetylcholinesterase, however this c...
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Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates
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TN_cdi_gale_infotracmisc_A613815101
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A613815101
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ISSN
0253-5106
DOI
10.52568/000606