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Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthio...

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A613815101

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates

About this item

Full title

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates

Publisher

Knowledge Bylanes

Journal title

Journal of the Chemical Society of Pakistan, 2020-02, Vol.42 (1), p.134-134

Language

English

Formats

Publication information

Publisher

Knowledge Bylanes

Subjects

Subjects and topics

More information

Scope and Contents

Contents

5-Arylidene-N,N-diethylthiobarbiturates 1-25 were evaluated for their potential against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes and displayed varying degree of inhibition. Based on the IC50 values, compound 6 (IC50 = 92.51 and#177; 0.01 and#181;M) was the only active compound against acetylcholinesterase, however this c...

Alternative Titles

Full title

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates

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Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A613815101

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A613815101

Other Identifiers

ISSN

0253-5106

DOI

10.52568/000606

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