ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin.sup.STAG1 from WAPL
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin.sup.STAG1 from WAPL
About this item
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Author / Creator
Wutz, Gordana , Ladurner, Rene , St Hilaire, Brian Glenn , Stocsits, Roman R , Nagasaka, Kota , Pignard, Benoit , Sanborn, Adrian , Tang, Wen , Várnai, Csilla , Ivanov, Miroslav P , Schoenfelder, Stefan , van der Lelij, Petra , Huang, Xingfan , Dürnberger, Gerhard , Roitinger, Elisabeth , Mechtler, Karl , Davidson, Iain Finley , Fraser, Peter , Lieberman-Aiden, Erez and Peters, Jan-Michael
Publisher
eLife Science Publications, Ltd
Journal title
Language
English
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Publisher
eLife Science Publications, Ltd
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Scope and Contents
Contents
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin's chromatin residence time to minutes, it has been reported that some loops exist for hours. How these loops can...
Alternative Titles
Full title
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin.sup.STAG1 from WAPL
Authors, Artists and Contributors
Author / Creator
Ladurner, Rene
St Hilaire, Brian Glenn
Stocsits, Roman R
Nagasaka, Kota
Pignard, Benoit
Sanborn, Adrian
Tang, Wen
Várnai, Csilla
Ivanov, Miroslav P
Schoenfelder, Stefan
van der Lelij, Petra
Huang, Xingfan
Dürnberger, Gerhard
Roitinger, Elisabeth
Mechtler, Karl
Davidson, Iain Finley
Fraser, Peter
Lieberman-Aiden, Erez
Peters, Jan-Michael
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A616108537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A616108537
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.52091
