H3K27me3-mediated PGC1[alpha] gene silencing promotes melanoma invasion through WNT5A and YAP
H3K27me3-mediated PGC1[alpha] gene silencing promotes melanoma invasion through WNT5A and YAP
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Publisher
American Society for Clinical Investigation
Journal title
Language
English
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Publisher
American Society for Clinical Investigation
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Contents
Oncogene-targeted and immune checkpoint the rapies have revolutionized the clinical management of malignant melanoma and now offer hope to patients with advanced disease. Intimately connected to patients' overall clinical risk is whether the initial primary melanoma lesion will metastasize and cause advanced disease, but underlying mechanisms are n...
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Full title
H3K27me3-mediated PGC1[alpha] gene silencing promotes melanoma invasion through WNT5A and YAP
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TN_cdi_gale_infotracmisc_A616904137
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A616904137
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI130038
