PTGES/PGE.sub.2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
PTGES/PGE.sub.2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
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Nature Publishing Group
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English
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Nature Publishing Group
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Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. However, due to lack of a relevant animal model for characterization, the underlying mechanism remains elusive. Lung tumor suppressor gene Gprc5a-knockout (ko) mice are susceptible to lung inflammation, tumorigenesis and metastasis, which resembles the pathol...
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PTGES/PGE.sub.2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
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TN_cdi_gale_infotracmisc_A619849763
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A619849763
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ISSN
0950-9232
DOI
10.1038/s41388-020-1207-6
