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A small nuclear acidic protein attenuates TNF-[alpha] inhibition of BMP-induced osteogenesis by enha...

A small nuclear acidic protein attenuates TNF-[alpha] inhibition of BMP-induced osteogenesis by enha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A624707097

A small nuclear acidic protein attenuates TNF-[alpha] inhibition of BMP-induced osteogenesis by enhancing accessibility of the Smad4-NF-[kappa]B p65 complex to Smad binding element

About this item

Full title

A small nuclear acidic protein attenuates TNF-[alpha] inhibition of BMP-induced osteogenesis by enhancing accessibility of the Smad4-NF-[kappa]B p65 complex to Smad binding element

Publisher

Springer

Journal title

Molecular and cellular biochemistry, 2020-06, Vol.469 (1-2), p.133

Language

English

Formats

Publication information

Publisher

Springer

More information

Scope and Contents

Contents

Pro-inflammatory cytokines prevent bone regeneration in vivo and activation of nuclear factor-[kappa]B (NF-[kappa]B) signaling has been proposed to lead to suppression of bone morphogenetic protein (BMP)-induced osteogenesis via direct binding of p65 to Smad4 in vitro. Application of a small nuclear acidic protein (MTI-II) and its delivered peptide...

Alternative Titles

Full title

A small nuclear acidic protein attenuates TNF-[alpha] inhibition of BMP-induced osteogenesis by enhancing accessibility of the Smad4-NF-[kappa]B p65 complex to Smad binding element

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A624707097

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A624707097

Other Identifiers

ISSN

0300-8177

DOI

10.1007/s11010-020-03734-6

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