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Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two...

Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A627434729

Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2.sup.C342Y/+ mouse models of Crouzon syndrome

About this item

Full title

Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2.sup.C342Y/+ mouse models of Crouzon syndrome

Publisher

Public Library of Science

Journal title

PloS one, 2020-05, Vol.15 (5), p.e0234073

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2.sup.C342Y/+ model of neonatal onset craniosynostosis or a BALB/c FGFR2.sup.C342Y/+ model of postnat...

Alternative Titles

Full title

Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2.sup.C342Y/+ mouse models of Crouzon syndrome

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A627434729

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A627434729

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0234073

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