Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two...
Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2.sup.C342Y/+ mouse models of Crouzon syndrome
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Public Library of Science
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English
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Public Library of Science
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Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2.sup.C342Y/+ model of neonatal onset craniosynostosis or a BALB/c FGFR2.sup.C342Y/+ model of postnat...
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Full title
Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2.sup.C342Y/+ mouse models of Crouzon syndrome
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TN_cdi_gale_infotracmisc_A627434729
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A627434729
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234073