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Inhibiting the NF-[kappa]B pathway enhances the antitumor effect of cabazitaxel by downregulating Bc...

Inhibiting the NF-[kappa]B pathway enhances the antitumor effect of cabazitaxel by downregulating Bc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A628079227

Inhibiting the NF-[kappa]B pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer

About this item

Full title

Inhibiting the NF-[kappa]B pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer

Publisher

Spandidos Publications

Journal title

International journal of oncology, 2020-07, Vol.57 (1), p.161

Language

English

Formats

Publication information

Publisher

Spandidos Publications

More information

Scope and Contents

Contents

Optimizing the currently available treatment options for pancreatic cancer (PC) is a priority. Cabazitaxel (CTX), a semisynthetic taxane, is mainly used for treating patients with PC who are resistant to paclitaxel (PTX) or docetaxel, due its poor affinity for P-glycoprotein. However, there are only a few studies demonstrating the effect of CTX on...

Alternative Titles

Full title

Inhibiting the NF-[kappa]B pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A628079227

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A628079227

Other Identifiers

ISSN

1019-6439

DOI

10.3892/ijo.2020.5053

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