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Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patien...

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patien...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A637398716

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients

About this item

Full title

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Oncology, 2016-11, Vol.91 (5), p.283-288

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Objective:Topoisomerase 1 (topo-1) is an important target for the treatment of metastatic colorectal cancer (CRC). The aim of the present study was to evaluate the correlation between topo-1 single-nucleotide polymorphisms (SNPs) and clinical outcome in metastatic CRC (mCRC) patients. Methods: With the use of specific software (PROMO 3.0), we perfo...

Alternative Titles

Full title

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A637398716

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A637398716

Other Identifiers

ISSN

0030-2414

E-ISSN

1423-0232

DOI

10.1159/000448004

How to access this item