Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress
Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress
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Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
Chronic exposure of [beta]-cells to nutrient-rich metabolic stress impairs mitochondrial metabolism and its coupling to insulin secretion. We exposed isolated human islets to different metabolic stresses for 3 days: 0.4 mM oleate or 0.4 mM palmitate at physiological 5.5 mM glucose (lipotoxicity), high 25 mM glucose (glucotoxicity), and high 25 mM g...
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Full title
Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress
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TN_cdi_gale_infotracmisc_A646135228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A646135228
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/bioml0111543
