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Microbial bile acid metabolites modulate gut ROR[gamma].sup.+ regulatory T cell homeostasis

Microbial bile acid metabolites modulate gut ROR[gamma].sup.+ regulatory T cell homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A648895936

Microbial bile acid metabolites modulate gut ROR[gamma].sup.+ regulatory T cell homeostasis

About this item

Full title

Microbial bile acid metabolites modulate gut ROR[gamma].sup.+ regulatory T cell homeostasis

Publisher

Nature Publishing Group

Journal title

Nature (London), 2020-01, Vol.577 (7790), p.410

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

The metabolic pathways encoded by the human gut microbiome constantly interact with host gene products through numerous bioactive molecules.sup.1. Primary bile acids (BAs) are synthesized within hepatocytes and released into the duodenum to facilitate absorption of lipids or fat-soluble vitamins.sup.2. Some BAs (approximately 5%) escape into the co...

Alternative Titles

Full title

Microbial bile acid metabolites modulate gut ROR[gamma].sup.+ regulatory T cell homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A648895936

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A648895936

Other Identifiers

ISSN

0028-0836

DOI

10.1038/s41586-019-1865-0

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