The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
About this item
Full title
Author / Creator
Publisher
American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
American Society for Clinical Investigation
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More information
Scope and Contents
Contents
Cutaneous melanoma remains the most lethal skin cancer, and ranks third among all malignancies in terms of years of life lost. Despite the advent of immune checkpoint and targeted therapies, only roughly half of patients with advanced melanoma achieve a durable remission. Sirtuin 5 (SIRT5) is a member of the sirtuin family of protein deacylases tha...
Alternative Titles
Full title
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
Authors, Artists and Contributors
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TN_cdi_gale_infotracmisc_A665893739
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A665893739
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI138926.
