Cytoskeleton Protein Filamin A Is Required for Efficient Somatostatin Receptor Type 2 Internalizatio...
Cytoskeleton Protein Filamin A Is Required for Efficient Somatostatin Receptor Type 2 Internalization and Recycling through Rab5 and Rab4 Sorting Endosomes in Tumor Somatotroph Cells
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Basel, Switzerland: S. Karger AG
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Language
English
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Basel, Switzerland: S. Karger AG
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Contents
The high expression of somatostatin receptor 2 (SST 2 ) in growth hormone (GH)-secreting tumors represents the rationale for the clinical use of somatostatin analogs (SSAs) in acromegaly. Recently, the cytoskeletal protein Filamin A (FLNA) has emerged as key modulator of the responsiveness of GH-secreting pituitary tumors to SSAs by regulating SST...
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Full title
Cytoskeleton Protein Filamin A Is Required for Efficient Somatostatin Receptor Type 2 Internalization and Recycling through Rab5 and Rab4 Sorting Endosomes in Tumor Somatotroph Cells
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TN_cdi_gale_infotracmisc_A667748615
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A667748615
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ISSN
0028-3835
E-ISSN
1423-0194
DOI
10.1159/000503791
