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Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-[beta]-induced fibrosis in...

Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-[beta]-induced fibrosis in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A688651294

Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-[beta]-induced fibrosis in human urothelial cells

About this item

Full title

Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-[beta]-induced fibrosis in human urothelial cells

Publisher

Spandidos Publications

Journal title

Experimental and therapeutic medicine, 2021-12, Vol.22 (6)

Language

English

Formats

Publication information

Publisher

Spandidos Publications

More information

Scope and Contents

Contents

Bladder outlet obstruction (BOO) is a common urological disease, and inhibition of TGF-[beta]-induced bladder tissue fibrosis may serve as an alternative strategy for BOO treatment. Aquaporin (AQP)2 was reported to be aberrantly expressed in rat BOO, but its specific role was not clarified. The aim of the present study was to explore the role of AQ...

Alternative Titles

Full title

Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-[beta]-induced fibrosis in human urothelial cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A688651294

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A688651294

Other Identifiers

ISSN

1792-0981

DOI

10.3892/etm.2021.10824

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